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arsanilic acid

CAS No.: 98-50-0      Formula: C6H8AsNO3

Weight: 217.05400

Synonyms: p-Arsanilic acid; (4-aminophenyl)arsonic acid; Arsonic acid, (4-aminophenyl)-;


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Description

Arsanilic acid, also known as aminophenyl arsenic acid or aminophenyl arsonic acid, is an organoarsenic compound, an amino derivative of phenylarsonic acid whose amine group is in the 4-position. A crystalline powder introduced medically in the late 19th century as Atoxyl, its sodium salt was used by injection in the early 20th century as the first organic arsenical drug, but it was soon found prohibitively toxic for human use. Arsanilic acid saw long use as a veterinary feed additive promoting growth and to prevent or treat dysentery in poultry and swine. In 2013, its approval by US government as an animal drug was voluntarily withdrawn by its sponsors. Still sometimes used in laboratories, arsanilic acid's legacy is principally through its influence on Paul Ehrlich in launching the chemotherapeutic approach to treating infectious diseases of humans.

Basic Information
CAS No.:
98-50-0
Synonyms:
p-Arsanilic acid; (4-aminophenyl)arsonic acid; Arsonic acid, (4-aminophenyl)-;
Formula:
C6H8AsNO3
Molecular Weight:
217.05400
PSA:
83.55000
LogP:
-0.58900
Properties
Appearance & Character:
Density:
white crystalline powder
Melting Point:
≥300 °C(lit.)
Boiling Point:
528.5ºC at 760 mmHg
Flash Point:
273.4ºC
Storage Conditions:
Safety Info
Customs Code:
29310095
WGK Germany:
3
Hazard Category Code:
R23/25; R50/53
Security Instructions:
S20/21-S28-S45-S60-S61-S28A
Dangerous Goods Sign:
T; N